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NiceZyme View of ENZYME: EC 1.1.1.21

Official Name
Aldehyde reductase.
Alternative Name(s)
Aldose reductase.
Polyol dehydrogenase (NADP(+)).
Reaction catalysed
Alditol + NAD(P)(+) <=> aldose + NAD(P)H
Comment(s)
  • Wide specificity.
  • Formerly EC 1.1.1.139.
Cross-references
Biochemical Pathways; map number(s)C3 ; C6
PROSITEPDOC00061
BRENDA1.1.1.21
PUMA21.1.1.21
PRIAM enzyme-specific profiles1.1.1.21
KEGG Ligand Database for Enzyme Nomenclature1.1.1.21
IUBMB Enzyme Nomenclature1.1.1.21
IntEnz1.1.1.21
MEDLINEFind literature relating to 1.1.1.21
MetaCyc1.1.1.21
UniProtKB/Swiss-Prot
P21300, ALD1_MOUSE;  O08782, ALD2_CRIGR;  P45377, ALD2_MOUSE;  
P16116, ALDR_BOVIN;  P23901, ALDR_HORVU;  P15121, ALDR_HUMAN;  
P45376, ALDR_MOUSE;  P80276, ALDR_PIG;  P15122, ALDR_RABIT;  
P07943, ALDR_RAT;  Q6IMN8, ALRA_DICDI;  Q54NZ7, ALRB_DICDI;  
Q55FL3, ALRC_DICDI;  P38715, GRE3_YEAST;  

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