| Official Name |
| Estradiol 17-beta-dehydrogenase.
|
| Alternative Name(s) |
| 17-beta-estradiol dehydrogenase. |
| 17-beta-HSD. |
| 17-beta-hydroxysteroid dehydrogenase. |
| 20-alpha-hydroxysteroid dehydrogenase. |
| Estrogen 17-oxidoreductase. |
| Reaction catalysed |
| Estradiol-17-beta + NAD(P)(+) <=> estrone + NAD(P)H |
| Comment(s) |
- Also acts on (S)-20-hydroxypregn-4-en-3-one and related compounds,
oxidizing the (S)-20-group.
- B-specific with respect to NAD(P)(+) (cf. EC 1.1.1.149).
|
| Cross-references |
| Biochemical Pathways; map number(s) | K9 ; K10 |
| PROSITE | PDOC00060 |
| BRENDA | 1.1.1.62 |
| PUMA2 | 1.1.1.62 |
| PRIAM enzyme-specific profiles | 1.1.1.62 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.1.1.62 |
| IUBMB Enzyme Nomenclature | 1.1.1.62 |
| IntEnz | 1.1.1.62 |
| MEDLINE | Find literature relating to 1.1.1.62 |
| MetaCyc | 1.1.1.62 |