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NiceZyme View of ENZYME: EC 1.1.1.62

Official Name
Estradiol 17-beta-dehydrogenase.
Alternative Name(s)
17-beta-estradiol dehydrogenase.
17-beta-HSD.
17-beta-hydroxysteroid dehydrogenase.
20-alpha-hydroxysteroid dehydrogenase.
Estrogen 17-oxidoreductase.
Reaction catalysed
Estradiol-17-beta + NAD(P)(+) <=> estrone + NAD(P)H
Comment(s)
  • Also acts on (S)-20-hydroxypregn-4-en-3-one and related compounds, oxidizing the (S)-20-group.
  • B-specific with respect to NAD(P)(+) (cf. EC 1.1.1.149).
Cross-references
Biochemical Pathways; map number(s)K9 ; K10
PROSITEPDOC00060
BRENDA1.1.1.62
PUMA21.1.1.62
PRIAM enzyme-specific profiles1.1.1.62
KEGG Ligand Database for Enzyme Nomenclature1.1.1.62
IUBMB Enzyme Nomenclature1.1.1.62
IntEnz1.1.1.62
MEDLINEFind literature relating to 1.1.1.62
MetaCyc1.1.1.62

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