The Bioinformatics Core
Facility for Proteomics is an entity of the
Proteome
Informatics Group. Its mission is to provide the best available
technology in bioinformatics for proteomics to contribute to the
research programs of scientists at the Faculties of Medicine and
Sciences from the University of Geneva, in the whole Switzerland or
abroad. In doing this, the Bioinformatics Facility for Proteomics
provides a cost-effective means for investigators to have access to
sophisticated data analysis via the latest software. Assistance,
training and access to cutting-edge equipment and software are
essential leitmotivs in the operation of the Bioinformatics Facility
for Proteomics, which are implemented through:
Help desk - we supply skilled
personnel to aid in the
analysis and interpretation of proteomics data such as electrophoresis
and mass spectral data;
Programming - we develop and program
tailored tools and databases to help the proteomics analyses;
Training - we teach fundamental and
practical aspects of
bioinformatics for proteomics to interested users to leverage the more
efficient use of software and research objectives;
Latest technologies - we provide
up-to-date software and computers to the research community.
The Bioinformatics Core Facility for Proteomics provides the
following services:
Comparative analysis of populations of 2-DE gel
images and
the discovery of differentially expressed proteins;
Identification and characterization of proteins using mass
spectrometry data and validation of the obtained results;
Data standardisation according to MIAPE rules or for
submission to World-2DPAGE and PRIDE databases.
In depth proteomics data analysis including detailed
characterisation based on data mining techniques;
Access to data analysis platforms, software applications
and databases developed by the PIG or skilled by PIG members, as well
as to open source and commercial tools, such as Phenyx, Mascot,
X!Tandem, InSPecT, Popitam, MSight, Melanie;
Development of customized analysis tools (scripts and
programs);
Design and implementation of databases and web applications
(e.g., MySQL database and web-based client/server interfaces);
Database development for publishing 2-DE gel images on the
Internet/Intranet;
Support for investigators for solving problems concerning
data acquisition, management, analysis and storage;
Comprehensive training program covering the principles of
bioinformatics for proteomics as well as the practical aspects of
software, tools and database usability and data analysis.
The Bioinformatics Core Facility for Proteomics and the Proteomics Core
Facility work in close collaboration to provide complementary
services to the proteomics community.
Contact:
Patricia PALAGI
Swiss Institute of Bioinformatics
CMU, 1 Michel-Servet
CH-1211 Geneva 4
Switzerland
Email: Patricia.Palagi@isb-sib.ch
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