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The UniProtKB/Swiss-Prot Human Proteome Initiative
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HPI Status report

UniProtKB/Swiss-Prot Release 56.1 of 02-Sep-2008: 397539 entries (Release statistics)

Total number of manually annotated mammalian entries in UniProtKB/Swiss-Prot: 63,534

Total number of manually annotated HUMAN entries in UniProtKB/Swiss-Prot: 20,325

Annotation categories counts [total / unique] max per entry average per entry number of entries coverage
Additional isoforms due to alternative splicing, initiation or promoter usage: 13,475 33 0.66 7,121 35%
Variants (disease mutations and polymorphisms): 45,955 1305 2.26 8,960 44%
Post-translational modifications (experimentally proven or potential): 59,236 303 2.91 11,202 55%
References to published articles: 102,594 / 44,792 176 5.05 20,092 98%
Comment blocks: 110,389 / 40,319 32 5.43 19,594 96%
Feature lines: 475,635 4049 23.40 20,325 100%
Cross-references:
EMBL protein_ids: 129,038 / 128,523 723 6.35 20,199 99%
InterPro: 50,003 / 6,420 23 2.46 16,775 82%
PDB (3D-structures): 27,250 / 25,688 460 1.34 3,369 16%
MIM catalog of human genes and genetic disorders: 15,245 / 14,359 15 0.75 12,117 59%
HGNC gene nomenclature: 19,031 / 18,902 14 0.94 18,877 92%

Total number of manually annotated MOUSE entries in UniProtKB/Swiss-Prot: 15,915

Annotation categories counts [total / unique] max per entry average per entry number of entries coverage
Additional isoforms due to alternative splicing, initiation or promoter usage: 7,191 20 0.45 4,265 26%
Variants (disease mutations and polymorphisms): 1,160 37 0.07 361 2%
Post-translational modifications (experimentally proven or potential): 49,243 216 3.09 9,480 59%
References to published articles: 46,594 / 17,309 49 2.93 15,674 98%
Comment blocks: 79,647 / 31,730 22 5.00 15,549 97%
Feature lines: 244,549 612 15.37 15,915 100%
Cross-references:
EMBL protein_ids: 67,737 / 67,685 111 4.26 15,777 99%
InterPro: 40,907 / 6,251 18 2.57 13,897 87%
PDB (3D-structures): 4,550 / 4,255 224 0.29 867 5%
Mouse Genome Informatics: 15,748 / 15,682 12 0.99 15,696 98%

Total number of manually annotated RAT entries in UniProtKB/Swiss-Prot: 7,170

Annotation categories counts [total / unique] max per entry average per entry number of entries coverage
Additional isoforms due to alternative splicing, initiation or promoter usage: 1,367 18 0.19 767 10%
Variants (disease mutations and polymorphisms): 238 12 0.03 113 1%
Post-translational modifications (experimentally proven or potential): 25,050 204 3.49 4,777 66%
References to published articles: 14,945 / 9,279 25 2.08 6,744 94%
Comment blocks: 36,747 / 17,524 24 5.13 7,032 98%
Feature lines: 105,182 314 14.67 7,170 100%
Cross-references:
EMBL protein_ids: 14,629 / 14,614 152 2.04 7,095 98%
InterPro: 19,534 / 4,587 19 2.72 6,460 90%
PDB (3D-structures): 2,598 / 2,480 116 0.36 389 5%
Rat Genome Database: 7,050 / 7,030 3 0.98 7,045 98%

For more detailed information about the taxonomic distribution of UniProtKB/Swiss-Prot entries, see the corresponding section in the Release statistics.

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