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UniProtKB/Swiss-Prot entry A8GD46

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name GHRA_SERP5
Primary accession number A8GD46
Secondary accession numbers None
Integrated into Swiss-Prot on September 2, 2008
Sequence was last modified on November 13, 2007 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 10)
Name and origin of the protein
Protein name Glyoxylate/hydroxypyruvate reductase A
Synonyms EC 1.1.1.79
EC 1.1.1.81
2-ketoacid reductase
Gene name
Name: ghrA
OrderedLocusNames: Spro_1933
From
Serratia proteamaculans (strain 568) [TaxID: 399741] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Serratia.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Taghavi S., Newman L., Vangronsveld J., van der Lelie D., Richardson P.;
"Complete sequence of chromosome of Serratia proteamaculans 568.";
Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000826; ABV41036.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001478164.1; -.
3D structure databases
ModBase A8GD46.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from UniProtKB-KW).
GO:0005886; Cellular component: plasma membrane (inferred from electronic annotation from HAMAP).
GO:0048037; Molecular function: cofactor binding (inferred from electronic annotation from InterPro).
GO:0030267; Molecular function: glyoxylate reductase (NADP) activity (inferred from electronic annotation from HAMAP).
GO:0016618; Molecular function: hydroxypyruvate reductase activity (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_01666; -; 1.
PBIL [Tree]
InterPro IPR006140; D-isomer_2_OHA_DHase_NAD-bd.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF02826; 2-Hacid_dh_C; 1.
Pfam graphical view of domain structure.
PROSITE PS00065; D_2_HYDROXYACID_DH_1; FALSE_NEG.
PS00670; D_2_HYDROXYACID_DH_2; FALSE_NEG.
PS00671; D_2_HYDROXYACID_DH_3; 1.
ProtoNet A8GD46.
Genome annotation databases
GeneID 5606872; -.
GenomeReviews CP000826_GR; Spro_1933.
KEGG spe:Spro_1933; -.
CMR A8GD46; Spro_1933.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; NAD; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   313  313     Glyoxylate/hydroxypyruvate reductase A. PRO_0000348373
ACT_SITE   228   228        By similarity. 
ACT_SITE   276   276        Proton donor (By similarity). 
Sequence information
Length: 313 AA [This is the length of the unprocessed precursor] Molecular weight: 34642 Da [This is the MW of the unprocessed precursor] CRC64: EDEDACA97CA14D1C [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MNIIFYHPFF NAEEWLAGLS QRLPQAQVRA WQPGDDRPAD YALVWRPPHE MLANRGRLKG 

        70         80         90        100        110        120 
VFALGAGVDA ILEQERAYPG TLPAGVPLLR LEDTGMAQQM QEYALSYVLR YFRRFDEYQL 

       130        140        150        160        170        180 
LQQQQEWRPL DPHQQDNFTI GILGAGVLGK SVAQKLTAFG FNVRCWSRSP KQIDGVQSFA 

       190        200        210        220        230        240 
GAEQRAAFLD GVQLLINLLP NTPETAGILN QQLFAHLAPG AYLINLARGA HLVEDDLLQA 

       250        260        270        280        290        300 
LEQGQLAAAT LDVFVTEPLP QAHPFWRHPR VTITPHIAAI TLPQAAMDQI AANILALEAG 

       310 
QTPAGVVDVL LGY
A8GD46 in FASTA format

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